出品公司: | ATCC |
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菌種名稱: | ATCC48272, ATCC 48272 |
菌種又名: | C-10 |
菌株類型: | 頂頭孢霉Acremonium chrysogenum |
存儲人: | J Lein |
分離來源: | |
產品目錄號: | 48272 |
其他保藏庫編號: | BCRC31697,ATCC 48272 |
培養基: | ATCC® Medium 336: Potato dextrose agar (PDA) |
生長條件: | 24 ℃ |
生物安全等級: | 1 |
模式菌株: | 否 |
應用: | 科研,生產,主要用于產生5-(2-氨基己丙基)半胱氨酸纈氨酸合成酶ACV合成酶,產生頭孢菌素C,生產脫乙酰氧基頭孢菌素C合成酶,生產異青霉素N合成酶,產:18000 mcg/ml頭孢菌素復合培養基 |
菌株特點: |
ATCC 48272是 頂頭孢霉Acremonium chrysogenum 。 |
參考文獻: |
Hollander IJ, et al. A pure enzyme catalyzing penicillin biosynthesis. Science 224: 610-612, 1984. PubMed: 6546810
Shen YQ, et al. Levels of isopenicillin N synthase and deacetoxycephalosporin C synthase in Cephalosporium acremonium producing high and low levels of cephalosporin C. Bio-Technology 4: 61-64, 1986.
Zhang J, et al. Carbon source regulation of ACV synthetase in Cephalosporium acremonium C-10. Curr. Microbiol. 18: 361-367, 1989.
Malmberg LH, Hu WS. Identification of rate-limiting steps in cephalosporin C biosynthesis in Cephalosporium acremonium: a theoretical analysis. Appl. Microbiol. Biotechnol. 38: 122-128, 1992. PubMed: 1369008
Zhang J, Demain AL. Regulation of ACV synthetase activity in the beta-lactam biosynthetic pathway of carbon sources and their metabolites. Arch. Microbiol. 158: 364-369, 1992.
Luengo JM, et al. Direct enzymatic synthesis of penicillin G using cyclases of Penicillium chrysogenum and Acremonium chrysogenum. Bio-Technology 4: 44-47, 1986.
Shen YQ, et al. Desacetoxycephalosporin C synthetase: importance of order of cofactor/reactant addition. Enzyme Microb. Technol. 6: 402-404, 1984.
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